Nichyle is the romantic pairing of Kyle Broflovski and minor character Nichole.
In "Cartman Finds Love", Nichole reveals that she originally had interest in Kyle at Bebe Stevens' sleepover party. Cartman thwarted this by manipulating Nichole in to believing that he and Kyle were in a homosexual relationship with each other. After Nichole ended her relationship with Token, Kyle took her to a basketball game.
This pairing has been overshadowed by the pairing of Nichole and Token Black in "Cartman Finds Love".